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Oxytocinase is a type of enzyme that metabolizes the endogenous neuropeptide, oxytocin. [1] The most well-characterized oxytocinase is leucyl/cystinyl aminopeptidase , [ 1 ] [ 2 ] which is also an enkephalinase .
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Parvocellular oxytocin cells, which project mainly to the brainstem and spinal cord. These neurons are thought to have a role in gastric reflexes and penile erection, [ 7 ] [ 8 ] Parvocellular vasopressin cells, which project to many points in the hypothalamus and limbic system , as well as to the brainstem and spinal cord (these are involved ...
Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the anterior pituitary. [1]: 719 The hypothalamus secretes tropic hormones that target the anterior pituitary, and the thyroid gland secretes thyroxine, which targets the hypothalamus and therefore can be considered a tropic hormone.
Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1] [2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3]
Image credits: AdamCSharp It’s important to supervise pets outside in freezing temperatures because if they’re left there too long, their body temperature can get dangerously low, increasing ...
Here hypothalamic neurosecretory cells release factors to the blood. Some of these factors (releasing hormones), released at the hypothalamic median eminence, control the secretion of pituitary hormones, while others (the hormones oxytocin and vasopressin) are released directly into the blood.