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  2. Theoretical plate - Wikipedia

    en.wikipedia.org/wiki/Theoretical_plate

    The theoretical plate in conventional distillation trays has no "height". It is simply a hypothetical equilibrium stage. However, the theoretical plate in packed beds, chromatography and other applications is defined as having a height.

  3. Van Deemter equation - Wikipedia

    en.wikipedia.org/wiki/Van_Deemter_equation

    Two well resolved peaks in a chromatogram. The plate height given as: = with the column length and the number of theoretical plates can be estimated from a chromatogram by analysis of the retention time for each component and its standard deviation as a measure for peak width, provided that the elution curve represents a Gaussian curve.

  4. Resolution (chromatography) - Wikipedia

    en.wikipedia.org/wiki/Resolution_(chromatography)

    The theoretical plate height is given by = where L is the column length and N the number of theoretical plates. [5] The relation between plate number and peak width ...

  5. Fenske equation - Wikipedia

    en.wikipedia.org/wiki/Fenske_equation

    Fractionation at total reflux. The Fenske equation in continuous fractional distillation is an equation used for calculating the minimum number of theoretical plates required for the separation of a binary feed stream by a fractionation column that is being operated at total reflux (i.e., which means that no overhead product distillate is being withdrawn from the column).

  6. Packed bed - Wikipedia

    en.wikipedia.org/wiki/Packed_bed

    The height equivalent to a theoretical plate (HETP) will be greater than expected. The problem is not the packing itself but the mal-distribution of the fluids entering the packed bed. These columns can contain liquid distributors and redistributors which help to distribute the liquid evenly over a section of packing, increasing the efficiency ...

  7. Fundamental resolution equation - Wikipedia

    en.wikipedia.org/wiki/Fundamental_Resolution...

    N = Number of theoretical plates. α = Selectivity Term = k 2 '/k 1 ' The [N 1/2 /4] term is the column factor, the [(α-1)/α] term is the thermodynamic factor, and the [k 2 '/(1+k 2 ')] term is the retention factor. The 3 factors are not completely independent, but they are very close, and can be treated as such. So what does this mean?

  8. High-performance liquid chromatography - Wikipedia

    en.wikipedia.org/wiki/High-performance_liquid...

    Peaks that are tall, sharp, and relatively narrow indicate that separation method efficiently removed a component from a mixture; high efficiency. Efficiency is very dependent upon the HPLC column and the HPLC method used. Efficiency factor is synonymous with plate number, and the 'number of theoretical plates'.

  9. McCabe–Thiele method - Wikipedia

    en.wikipedia.org/wiki/McCabe–Thiele_method

    The number of steps between the operating lines and the equilibrium line represents the number of theoretical plates (or equilibrium stages) required for the distillation. For the binary distillation depicted in Figure 1, the required number of theoretical plates is 6. Constructing a McCabe–Thiele diagram is not always straightforward.