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Latinos tend to have higher normal levels, followed by those of African heritage, Europeans, and Asians or Pacific Islanders tend to have the lowest baseline ALP levels (all groups assuming body mass index within normal weight range). [5] Men tend to have slightly higher normal ALP levels than women, [5] except during pregnancy.
Reference ranges (reference intervals ... Adult male and female: 60 [96] 270 [96] ng/dL ... The INR is a corrected ratio of a patient's PT to normal
Average male height Average female height Stature ratio (male to female) Sample population / age range Share of pop. over 18 covered [9] [10] [b] Method Year Ref. Afghanistan: 168.2 cm (5 ft 6 in) 155.3 cm (5 ft 1 in) 1.08: 18–69 (N= m:1,979 f:1,687) 97.2%: Measured: 2018 [11] Albania: 176.6 cm (5 ft 9 + 1 ⁄ 2 in) 166.8 cm (5 ft 5 + 1 ⁄ 2 ...
In alcoholic liver disease, the mean ratio is 1.45, and mean ratio is 1.33 in post necrotic liver cirrhosis. Ratio is greater than 1.17 in viral cirrhosis, greater than 2.0 in alcoholic hepatitis, and 0.9 in non-alcoholic hepatitis. Ratio is greater than 4.5 in Wilson disease or hyperthyroidism. [6]
Waist-to-height ratio: the average ratio for US college competitive swimmers is 0.424 (women) and 0.428 (men); the ratios for a (US) normally healthy man or woman is 0.46–0.53 and 0.45–0.49 respectively; the ratio ranges beyond 0.63 for morbidly obese individuals. [15]
The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.
The severity of symptoms ranges from premature loss of deciduous teeth with no bone abnormalities to stillbirth [18] depending upon which amino acid [19] [20] is changed in the ALPL gene. Mutations in the ALPL gene lead to varying low activity of the enzyme tissue-nonspecific alkaline phosphatase (TNSALP or TNAP) resulting in hypophosphatasia ...
Normal ranges for both ALT and AST vary by gender, age, and geography and are roughly 8-40 U/L (0.14-0.67 μkal/L). [4] Mild transaminesemia refers to levels up to 250 U/L. [ 1 ] Drug-induced increases such as that found with the use of anti-tuberculosis agents such as isoniazid are limited typically to below 100 U/L for either ALT or AST.