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It is the largest and most up-to-date source of information on drug products approved for use in Nigeria by NAFDAC (National Agency for Food & Drug Administration & Control). The use of EMDEX as a reference drug manual is endorsed by the Pharmacists Council of Nigeria, the Nursing & Midwifery Council of Nigeria, and major health institutions ...
Terconazole was the first triazole-based antifungal drug synthesized for human use. Janssen Pharmaceutica developed it in 1983. [21] Previously, all triazole based drugs targeted fungal infections related to plants from Candida species.
Some fungi (e.g. Candida krusei and fluconazole) exhibit intrinsic resistance to certain antifungal drugs or classes, whereas some species develop antifungal resistance to external pressures. Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals ...
Antifungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). [15]
Nystatin is commonly used in treatment of lesions of the mouth caused by oral candidiasis. The drug can be formulated in pastilles or suspensions and is directly applied to the affected area. After application, patients should avoid taking food or drink for an hour to allow sufficient time for the drug to exert its effect locally. Oral ...
It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1] It may also be used to prevent candidiasis in those who are at high risk. [1] Nystatin may be used by mouth, in the vagina, or applied to the skin. [1]
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. [11] Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. [12]
The National Agency for Food and Drug Administration and Control (NAFDAC) is a Nigerian federal agency under the Federal Ministry of Health that is responsible for regulating and controlling the manufacture, importation, exportation, advertisement, distribution, sale, and use of food, drugs, cosmetics, medical devices, chemicals, and packaged water.