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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    The effectiveness of PPIs has not been demonstrated for every case. For example, although they reduce the incidence of esophageal adenocarcinoma in Barrett's oesophagus, [16] they do not change the length affected. [25] In addition, research in the UK has suggested that PPIs are not effective at treating persistent throat symptoms. [26] [27]

  3. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia. [ 6 ] However, this remain controversial as chronic and co-morbid pathology, and resultant polypharmacy (including increased consumption of PPIs), will probably itself also ...

  4. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    If symptoms of discontinuation are severe, or do not respond to symptom management, the antidepressant can be reinstated and then withdrawn more cautiously, or by switching to a drug with a longer half life (e.g., fluoxetine), and then tapering and discontinuing that drug. [21] In severe cases, hospitalization may be required. [2]

  5. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    The symptoms from withdrawal may be even more dramatic when the drug has masked prolonged malnutrition, disease, chronic pain, infections (common in intravenous drug use), or sleep deprivation, conditions that drug abusers often develop as a secondary consequence of the drug. When the drug is removed, these conditions may resurface and be ...

  6. List of medical symptoms - Wikipedia

    en.wikipedia.org/wiki/List_of_medical_symptoms

    [1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.

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  8. Indigestion - Wikipedia

    en.wikipedia.org/wiki/Indigestion

    A negative test warrants discussing additional treatments, like proton pump inhibitors, with your doctor. [1] An upper GI endoscopy may also be recommended. [ 29 ] In older patients (60 or older), an endoscopy is often the next step in finding out the cause of newly onset indigestion regardless of the presence of alarm symptoms. [ 1 ]

  9. Gastroesophageal reflux disease - Wikipedia

    en.wikipedia.org/wiki/Gastroesophageal_reflux...

    Proton-pump inhibitors (PPIs), such as omeprazole, are the most effective, followed by H 2 receptor blockers, such as ranitidine. [43] If a once-daily PPI is only partially effective they may be used twice a day. [43] They should be taken one half to one hour before a meal. [42] There is no significant difference between PPIs. [42]