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The cortex of a lymph node is the outer portion of the node, underneath the capsule and the subcapsular sinus. [17] It has an outer part and a deeper part known as the paracortex. [17] The outer cortex consists of groups of mainly inactivated B cells called follicles. [5] When activated, these may develop into what is called a germinal centre. [5]
The substance of a lymph node consists of lymphoid follicles in an outer portion called the cortex. The inner portion of the node is called the medulla , which is surrounded by the cortex on all sides except for a portion known as the hilum .
Lymph nodes of the lungs: The lymph is drained from the lung tissue through subsegmental, segmental, lobar and interlobar lymph nodes to the hilar lymph nodes, which are located around the hilum (the pedicle, which attaches the lung to the mediastinal structures, containing the pulmonary artery, the pulmonary veins, the main bronchus for each side, some vegetative nerves and the lymphatics) of ...
A lymph node is small, capsulated lymphoid organ that is present along the lymphatic system. It is composed of cortex and medulla. The cortex is also divided into outer cortex and inner cortex (also known as the paracortex). The outer cortex is composed of follicles of B cells so that it is called the B-cell zone.
Lymph (from Latin lympha 'water') [1] is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues to be recirculated.
Lymph node stromal cells are essential to the structure and function of the lymph node whose functions include: creating an internal tissue scaffold for the support of hematopoietic cells; the release of small molecule chemical messengers that facilitate interactions between hematopoietic cells; the facilitation of the migration of hematopoietic cells; the presentation of antigens to immune ...
Cortical bone is the hard outer layer of bone; distinct from the spongy, inner cancellous bone tissue [2] Ovarian cortex is the outer layer of the ovary and contains the follicles. The lymph node cortex is the outer layer of the lymph node.
Germinal centers are initiated in the B cell follicle of the lymph node. Following activation of naive B cells in the lymph node follicles, the B cells migrate to the interfollicular areas so that they can interact with T cells. When the B and T cells interact, the antigen-specific T cell receptors bind the antigen + MHC presented by the B cells.