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The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).
Please note the image (Fig 1) of the wells on the test plate and the positive and negative test results look different. [1] For primary syphilis, TPPA has a sensitivity of 85% to 100%, and a specificity of 98% to 100%. [2] In secondary and late-latent syphilis, TPPA has a sensitivity of 98% to 100%. [2]
The Wassermann test or Wassermann reaction (WR) [1] is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it.
Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Syphilis is most commonly spread through sexual activity. [2] It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis.
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The MHA-TP is used to confirm a syphilis infection after another method tests positive for the syphilis bacteria. The MHA-TP test detects antibodies to the bacteria that cause syphilis and can be used to detect syphilis in all stages, except during the first 3 to 4 weeks. This test is not done on spinal fluid.
With syphilis cases in U.S. newborns skyrocketing, a doctors group now recommends that all pregnant patients be screened three times for the sexually transmitted infection. The American College of ...
With syphilis cases in U.S. newborns skyrocketing, a doctors group now recommends that all pregnant patients be screened three times for the sexually transmitted infection. The American College of Obstetricians and Gynecologists issued new guidance on Thursday saying the screening should be done at the first prenatal visit, during the third ...