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Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
The styrene monomer (from which polystyrene is made) is a cancer suspect agent. [109] Styrene is "generally found in such low levels in consumer products that risks aren't substantial". [110] Polystyrene which is used for food contact may not contain more than 1% (0.5% for fatty foods) of styrene by weight. [111]
Residents near Cleves are being urged to leave their homes Tuesday afternoon because a rail car is leaking styrene. What to know about the chemical.
Styrene is a flammable gas and can be fatal if inhaled. The chemical is also considered a probable human carcinogen that can damage organs, inflame lungs, and make it hard to breathe, according to ...
Officials said a chemical reaction caused styrene, which is naturally a liquid, to heat up into a gaseous state. This chemical reaction caused the tank’s pressure valve to open and release gas ...
Poly(p-phenylene oxide) (PPO), poly(p-phenylene ether) (PPE), poly(oxy-2,6-dimethyl-1,4-phenylene), often referred to simply as polyphenylene oxide, is a high-temperature thermoplastic with the general formula (C 8 H 8 O) n. It is rarely used in its pure form due to difficulties in processing.
In enzymology, a styrene-oxide isomerase (EC 5.3.99.7) is an enzyme that catalyzes the chemical reaction styrene oxide ⇌ {\displaystyle \rightleftharpoons } phenylacetaldehyde Hence, this enzyme has one substrate , styrene oxide , and one product , phenylacetaldehyde .