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  2. GABA reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/GABA_reuptake_inhibitor

    A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]

  3. γ-Acetylenic GABA - Wikipedia

    en.wikipedia.org/wiki/Gamma-Acetylenic-GABA

    γ-Acetylenic GABA, also known as 4-aminohex-5-ynoic acid is a potent and irreversible inhibitor of GABA-T. [3] Mechanism of action

  4. Glutamate–glutamine cycle - Wikipedia

    en.wikipedia.org/wiki/Glutamate–glutamine_cycle

    The glutamate/GABA–glutamine cycle is a metabolic pathway that describes the release of either glutamate or GABA from neurons which is then taken up into astrocytes (non-neuronal glial cells). In return, astrocytes release glutamine to be taken up into neurons for use as a precursor to the synthesis of either glutamate or GABA. [2]

  5. N-Acetyl-γ-aminobutyric acid - Wikipedia

    en.wikipedia.org/wiki/N-Acetyl-γ-aminobutyric_acid

    [2] [3] [4] The pathway is a minor pathway in GABA synthesis compared to the main pathway in which GABA is synthesized from glutamate. [2] [3] [4] However, the pathway has been found to have an important physiological role in the brain, for instance in the production of GABA in the striatum and resultant inhibition of dopaminergic neurons in ...

  6. Gabaculine - Wikipedia

    en.wikipedia.org/wiki/Gabaculine

    Gabaculine is a naturally occurring neurotoxin first isolated from the bacteria Streptomyces toyacaensis, [1] which acts as a potent and irreversible GABA transaminase inhibitor, [2] [3] and also a GABA reuptake inhibitor. [4] [5] Gabaculine is also known as 3-amino-2,3-dihydrobenzoic acid hydrochloride [6] and 5-amino cyclohexa-1,3 dienyl ...

  7. Doctors Say This Is the Best Time to Take Iron Supplements - AOL

    www.aol.com/doctors-best-time-iron-supplements...

    The best time to take iron supplements. Ideally, you should take your iron supplement first thing in the morning and before foods or other medications to get the best results, ...

  8. When Is the Best Time to Take Your Vitamin D? - AOL

    www.aol.com/lifestyle/best-time-vitamin-d...

    The best time to take any vitamin is the time when you will remember, says Gans. In other words, there is no best time, and you can take it at any time of day that works best for your routine.

  9. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    As mentioned, the best time to take metformin really depends on your unique needs and how you react to the medication. The one constant here is that you should take it with food and water. So ...