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Epithelioid hemangioendothelioma (EHE) is a rare tumor, first characterized by Sharon Weiss and Franz Enzinger in 1982 [1] that both clinically and histologically is intermediate between angiosarcoma and hemangioma. However, a distinct, disease-defining genetic alteration recently described for EHE indicates that it is an entirely separate ...
Epithelioid hemangioendothelioma is an uncommon vascular tumor of intermediate malignancy that was first described by Steven Billings, Andrew Folpe, and Sharon Weiss in 2003. [1] These tumors are so named because their histologic appearance resembles a proliferation of epithelioid cells, with polygonal shape and eosinophilic cytoplasm.
Differential diagnosis includes vascular malformation, angioma, pyogenic granuloma, angiosarcoma, epithelioid hemangioendothelioma, Kaposi’s sarcoma, and other more rare vascular tumors. Three forms of intravascular papillary endothelial hyperplasia exist: the primary or pure form, the secondary or mixed form, and the extravascular form.
Kaposiform hemangioendothelioma. Kaposiform hemangioendotheliomas (KHEs) are borderline, locally destructive vascular tumors. [4] They are named after their resemblance to the lesions of Kaposi's sarcoma. [13] KHEs are described as locally destructive because they can infiltrate underlying muscle and fat. [4]
Survival rates for most childhood cancers have improved, with a notable improvement in acute lymphoblastic leukemia (the most common childhood cancer). Due to improved treatment, the 5-year survival rate for acute lymphoblastic leukemia has increased from less than 10% in the 1960s to about 90% during the time period 2003-2009.
Kaposiform hemangioendothelioma; M9130/3 Hemangioendothelioma, malignant Hemangioendothelial sarcoma; M9131/0 Capillary hemangioma Hemangioma simplex; Infantile/plexiform/juvenile hemangioma; M9132/0 Intramuscular hemangioma M9133/1 Epithelioid hemangioendothelioma, NOS M9133/3 Epithelioid hemangioendothelioma, malignant Intravascular bronchial ...
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