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Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. [1] This can cause heart failure, arrhythmia, myocarditis, and cardiomyopathy in patients. [2] Some effects are reversible, while in others, permanent damage requiring further treatment may arise. The heart becomes weaker and is not ...
It is distinguished from non-eosinophilic myocarditis, which is heart inflammation caused by other types of white blood cells, i.e. lymphocytes and monocytes, as well as the respective descendants of these cells, NK cells and macrophages. This distinction is important because the eosinophil-based disorder is due to a particular set of ...
Lung symptoms in a patient who is taking a medicinal drug that can cause pulmonary toxicity should not automatically lead to a diagnosis of "pulmonary toxicity due to the medicinal drug", because some patients can have another (i.e., simultaneous) lung disease, e.g. an infection of the lungs not related to the medicinal drugs the patient is ...
Heart murmurs may indicate the presence of valvular heart disease, either as a cause (e.g., aortic stenosis) or as a consequence (e.g., mitral regurgitation) of heart failure. [32] Reverse insufficiency of the left ventricle causes congestion in the blood vessels of the lungs so that symptoms are predominantly respiratory. Reverse insufficiency ...
Chronic Obstructive Pulmonary Disease (lung disease) [43] Gastrointestinal discomfort [44] Tachycardia (heart rate too fast) [44] Rapid drop in Weight [40] Headaches [40] Dizziness [40] Insomnia [40] Psychological disorder (for example anxiety) [45] Compromised liver or kidney function with drugs that inhibit an enzyme called CYP3A4 [46]
The restored blood flow reintroduces oxygen within cells that damages cellular proteins, DNA, and the plasma membrane. Damage to the cell's membrane may in turn cause the release of more free radicals. Such reactive species may also act indirectly in redox signaling to turn on apoptosis. White blood cells may also bind to the endothelium of ...
If taken during pregnancy or breastfeeding it can cause problems in the fetus or the infant. [4] It is a class III antiarrhythmic medication. [4] It works partly by increasing the time before a heart cell can contract again. [4] [6] Amiodarone was first made in 1961 and came into medical use in 1962 for chest pain believed to be related to the ...
Pulmonary heart disease, also known as cor pulmonale, is the enlargement and failure of the right ventricle of the heart as a response to increased vascular resistance (such as from pulmonic stenosis) or high blood pressure in the lungs. [2] Chronic pulmonary heart disease usually results in right ventricular hypertrophy (RVH), [4] whereas ...
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