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Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
The bulb portion is thinner and therefore "squeezable", while the pipette portion is thick enough to be rigid. They commonly come in 1, 2, 3, and 5 ml which comes with a specific drop size of 10, 20, 25, 35, and 50 μL. [7] The volumes are usually marked on the stem, though the markings are rather crude and are not particularly accurate. [8]
Drug instillation, also known as medication instillation, is the administration of a medicine, generally in liquid form either drop by drop or with a catheter into a body space or cavity. [1] Drop by drop administration may be done for eye drops , ear drops , or nose drops . [ 1 ]
administration: Eye drops [1] ATC code: A01AB10 ... Solubility in water: 0.39 mg/ml: ... a dose of 500 mg/kg/day repeated over multiple days caused nausea, vomiting ...
Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation ...
The minim was defined as one 60th of a fluid dram or one 480th of a fluid ounce. [5] This is equal to about 61.6 μL (U.S.) or 59.2 μL (Britain). Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter).