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Fibroadenoma of the breast is a benign tumor composed of a biplastic proliferation of both stromal and epithelial components. [ 12 ] [ 13 ] This biplasia can be arranged in two growth patterns: pericanalicular (stromal proliferation around epithelial structures) and intracanalicular (stromal proliferation compressing the epithelial structures ...
The periareolar glands of Montgomery in the breast are also called Montgomery tubercles or Morgagni tubercles. These periareolar glands are small, papular tissue projections at the edge of the areola (nipple).Obstruction of the Montgomery tubercles may result in an acute inflammation, a clear or light brownish fluid may drain out of the areola (nipple discharge), and an subareolar mass may ...
Fibrocystic breast changes is a condition of the breasts where there may be pain, breast cysts, and breast masses. [1] The breasts may be described as "lumpy" or "doughy". [3] Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. [1] These are normal breast changes, not associated with cancer. [2]
Worldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases. [5] It is most common in women over age 50. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. [6]
The Annals study estimated that significant numbers of women over 70 are potentially overdiagnosed for breast cancer, including nearly half of those aged 75 to 84.
A breast mass, also known as a breast lump, is a localized swelling that feels different from the surrounding tissue. [1] Breast pain, nipple discharge, or skin changes may be present. [1] Concerning findings include masses that are hard, do not move easily, are of an irregular shape, or are firmly attached to surrounding tissue. [2]
Breast pain is the symptom of discomfort in either one or both breasts. [2] Pain in both breasts is often described as breast tenderness, is usually associated with the menstrual period and is not serious. [1] [3] Pain that involves only one part of a breast is more concerning, [1] particularly if a hard mass or nipple discharge is also present ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.