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The hippocampal formation is a compound structure in the medial temporal lobe of the brain. It forms a c-shaped bulge on the floor of the inferior horn of the lateral ventricle . [ 1 ] Typically, the hippocampal formation is said to included the dentate gyrus , the hippocampus , and the subiculum . [ 2 ]
In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system. The hippocampus plays important roles in the consolidation of information from short-term memory to long-term memory , and in spatial memory that enables navigation .
The hippocampus is located in the medial temporal lobe (subcortical), and is an infolding of the medial temporal cortex. [1] The hippocampus plays an important role in the transfer of information from short-term memory to long-term memory during encoding and retrieval stages. These stages do not need to occur successively, but are, as studies ...
To further distinguish age-related memory loss from Alzheimer's disease (AD), a subregion of the hippocampal formation called the dentate gyrus (DG) was further studied, since it is thought to be targeted by aging. Human postmortem tissue was collected from both DG and entorhinal cortex (EC). Entorhinal cortex is a neighboring subregion ...
The hippocampus is a structure in the brain that has been associated with various memory functions. It is part of the limbic system, and lies next to the medial temporal lobe. It is made up of two structures, the Ammon's Horn, and the Dentate gyrus, each containing different types of cells. [1]
The archicortex is most prevalent in the olfactory cortex and the hippocampus, [4] which are responsible for processing smells and forming memories, respectively. [5] Because olfaction is considered to be the phylogenetically oldest sensory modality, [6] and the limbic system, of which the hippocampus is a part, is one of the oldest systems in the brain, [7] it is likely that the archicortex ...
The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation.The hippocampal formation is located in the temporal lobe of the brain, and includes the hippocampus (including CA1 to CA4) subfields, and other subfields including the dentate gyrus, subiculum, and presubiculum.
Thus, a damaged hippocampus can cause memory loss and inability of cognitive function. Furthermore, as the hippocampus is the region controlling learning and memory processes, the research on Schaffer collaterals may help to find treatments for diseases related to the hippocampus or its neural processing pathways such as Alzheimer's disease, a ...