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[12] [13] [14] One interpretation is that depression manifests due to an imbalance of neurotransmitters in the brain, resulting in feelings of worthlessness and despair. Magnetic resonance imaging shows that the brains of people diagnosed with depression may have a hippocampus up to 10% smaller than those who do not exhibit signs of depression.
Feeling sad for no reason may happen due to depression, stress, sleep deprivation, grief, and other reasons. Learn all the potential causes, as well as tips for coping.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
One factor that causes mood disturbance is fluctuation of milieu hormones [143] including sex steroids, growth hormones, stress hormones, etc. [144] [145] Major depression : Major depression is a disorder with symptoms such as feelings of sadness, loss of interest, emptiness [ 146 ] and, for some people, mixed with irritability, mental ...
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Causes: Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1]
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