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Iron(III)-hydroxide polymaltose complex is a medication used to treat iron deficiency / iron deficiency anemia and belongs to the group of oral iron preparations.The preparation is a macromolecular complex, consisting of iron(III) hydroxide (trivalent iron, Fe 3+, Fe(OH) 3 ·H 2 O) and the carrier polymaltose and is available in solid form as a film-coated or chewable tablet and in liquid form ...
Different dosage forms of iron preparation have different absorption mechanisms. Iron in oral iron preparations is absorbed in the gut via transporters and carrier proteins and released to the bloodstream. [3] Iron in parenteral iron preparation needs to be released by the cleavage of the surrounding complex by macrophages. [4]
The most common side effects are headaches which occur in 3.3%, and hypophosphatemia, which occurs in more than 35%. [ 8 ] [ 9 ] Iron isomaltoside 1000 (brand name Monofer) is a formulation of parenteral iron that has a matrix structure that results in very low levels of free iron and labile iron.
[1] [2] [3] Subgroup B03 is part of the anatomical group B Blood and blood forming organs. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QB03. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
The therapeutic dose for iron deficiency anemia is 3–6 mg/kg/day. Individuals who have ingested less than 20 mg/kg of elemental iron typically do not exhibit symptoms. [4] It is unlikely to get iron poisoning from diet alone with iron supplements being the cause of overdose.
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