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Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.
Interleukin 6 (IL6), also referred to as B-cell stimulatory factor-2 (BSF-2) and interferon beta-2, is a cytokine involved in a wide variety of biological functions. [20] It plays an essential role in the final differentiation of B cells into immunoglobulin-secreting cells, as well as inducing myeloma/plasmacytoma growth, nerve cell ...
The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [6] IL6R subunit is also shared by many other cytokines.
In fact, eccentric exercise may result in a delayed peak and a much slower decrease of plasma IL-6 during recovery. [23] Anti-IL-6 therapies should therefore take into consideration the (beneficial) anti-inflammatory effects of myokines generally, including the now-established multiple benefits of muscle-derived Interleukin 6. [23]
Hyper-IL-6 is a designer cytokine, which was generated by the German biochemist Stefan Rose-John. [1] Hyper-IL-6 is a fusion protein of the four-helical cytokine Interleukin-6 and the soluble Interleukin-6 receptor which are covalently linked by a flexible peptide linker. [1] Interleukin-6 on target cells binds to a membrane bound Interleukin-6 ...
A quiz is a form of mind sport in which people attempt to answer questions correctly on one or several topics. Quizzes can be used as a brief assessment in education and similar fields to measure growth in knowledge, abilities, and skills, or simply as a hobby .
Interleukin 17 family (IL17 family) is a family of pro-inflammatory cystine knot cytokines. [2] They are produced by a group of T helper cell known as T helper 17 cell in response to their stimulation with IL-23.
Glycoprotein 130 (also known as gp130, IL6ST, IL6R-beta or CD130) is a transmembrane protein which is the founding member of the class of tall cytokine receptors.It forms one subunit of the type I cytokine receptor within the IL-6 receptor family.