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Ehrlichiosis is a nationally notifiable disease in the United States. Cases have been reported in every month of the year, but most cases are reported during April–September. [22] [23] [24] These months are also the peak months for tick activity in the United States. [7] The majority of cases of Ehrlichiosis tend to be in the United States.
Human monocytotropic ehrlichiosis occurs in California in Ixodes pacificus ticks and in Dermacentor variabilis ticks. [14] Nearly 600 cases were reported to the CDC in 2006. In 2001–2002, the incidence was highest in Missouri, Tennessee, and Oklahoma, as well as in people older than 60.
Ehrlichia chaffeensis. E. chaffeensis causes human monocytic ehrlichiosis and is known to infect monocytes. [1] It has also been known to infect other cell types such as lymphocytes, atypical lymphocytes, myelocytes, and neutrophils, but monocytes appear to best harbor the infection.
These bacteria cause the disease ehrlichiosis, which is considered zoonotic, because the main reservoirs for the disease are animals. Ehrlichia species are obligately intracellular pathogens and are transported between cells through the host cell filopodia during initial stages of infection, whereas in the final stages of infection, the ...
There are four documented manifestations of the disease, these are acute, peracute, subacute, and a mild form known as heartwater fever. There are reports of zoonotic infections of humans by E. ruminantium, similar to other Ehrlichia species, such as those that cause human ehrlichiosis. [4] [5] [6]
Ehrlichia ewingii is a human pathogen which results in a serious infection if not treated in a timely manner. [7] Ehrlichiosis, the disease caused by E. ewingii and E. chaffeensis, presents with fever, headache, fatigue, and muscle aches. [8] These symptoms are extremely unspecific which makes the infections difficult to diagnose. [8]
Ehrlichiosis ewingii infection [1] is an infectious disease caused by an intracellular bacteria, Ehrlichia ewingii. [2] The infection is transmitted to humans by the tick, Amblyomma americanum . This tick can also transmit Ehrlichia chaffeensis , the bacteria that causes human monocytic ehrlichiosis (HME).
Anaplasma phagocytophilum (formerly Ehrlichia phagocytophilum) [2] is a Gram-negative bacterium that is unusual in its tropism to neutrophils.It causes anaplasmosis in sheep and cattle, also known as tick-borne fever and pasture fever, and also causes the zoonotic disease human granulocytic anaplasmosis.