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  2. Anterior cruciate ligament reconstruction - Wikipedia

    en.wikipedia.org/wiki/Anterior_cruciate_ligament...

    This involves repairing the ACL by re-attaching it, instead of performing a reconstruction. Theoretical advantages of repair include faster recovery [2] and a lack of donor site morbidity, but randomised controlled trials and long-term data regarding re-rupture rates using contemporary surgical techniques are lacking.

  3. Anterior cruciate ligament injury - Wikipedia

    en.wikipedia.org/wiki/Anterior_cruciate_ligament...

    Nevertheless, ACL tears alone increase inflammatory markers in the knee which can have influence on the development of osteoarthritis. [63] Young female athletes have a significant risk of re-tearing an ACL graft, or tearing the ACL on the other knee after their recovery. This risk has been recorded as being nearly 1 out of every 4 young ...

  4. Accelerated life testing - Wikipedia

    en.wikipedia.org/wiki/Accelerated_life_testing

    Accelerated life testing is the process of testing a product by subjecting it to conditions (stress, strain, temperatures, voltage, vibration rate, pressure etc.) in excess of its normal service parameters in an effort to uncover faults and potential modes of failure in a short amount of time.

  5. Unhappy triad - Wikipedia

    en.wikipedia.org/wiki/Unhappy_triad

    The unhappy triad, also known as a blown knee among other names, is an injury to the anterior cruciate ligament, medial collateral ligament, and meniscus.Analysis during the 1990s indicated that this 'classic' O'Donoghue triad is actually an unusual clinical entity among athletes with knee injuries.

  6. Bone remodeling period - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling_period

    In calculating the bone remodeling period, a two-dimensional model is examined, referring to the time it takes for the area in question to be eroded and then filled in with new bone (sigma will be used here for simplicity's sake). The bone formation portion (σ f) of the bone remodeling period is calculated as follows: [5]

  7. Accelerated failure time model - Wikipedia

    en.wikipedia.org/wiki/Accelerated_failure_time_model

    In full generality, the accelerated failure time model can be specified as [2] (|) = ()where denotes the joint effect of covariates, typically = ⁡ ([+ +]). (Specifying the regression coefficients with a negative sign implies that high values of the covariates increase the survival time, but this is merely a sign convention; without a negative sign, they increase the hazard.)

  8. Accelerated approval (FDA) - Wikipedia

    en.wikipedia.org/wiki/Accelerated_approval_(FDA)

    Drugs with accelerated approval can initially be tested in clinical trials that use a surrogate endpoint, or something that is thought to predict clinical benefit. Surrogate endpoints typically require less time, and in the case of a cancer patient, it is much faster to measure a reduction in tumor size, for example, than overall patient survival.

  9. Post-anesthesia care unit - Wikipedia

    en.wikipedia.org/wiki/Post-anesthesia_care_unit

    A post-anesthesia care unit (PACU) and sometimes referred to as post-anesthesia recovery or PAR, or simply recovery, is a part of hospitals, ambulatory care centers, and other medical facilities. Patients who received general anesthesia , regional anesthesia , or local anesthesia are transferred from the operating room suites to the recovery area.