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In vitro muscle testing can be done on any scale of muscle organization - entire groups of muscles (provided they share a common insertion or origin, as in the human quadriceps), a single muscle, a "bundle" of muscle fibers, a single muscle fiber, a single myofibril, a single sarcomere, a cardiomyocyte or even a half-sarcomere. Muscle fibers ...
Tensiomyography data can be used to determine muscle fiber type (e.g., by comparing displacement signal and muscle histochemistry [3] / heavy chain myosin amount20) and muscle status/condition (e.g.,fatigue, [4] potentiation, [5] inhibition, stress influence on the body, etc.), to diagnose functional muscular symmetry, either temporal or ...
Sarcoplasm is the cytoplasm of a muscle cell. It is comparable to the cytoplasm of other cells, but it contains unusually large amounts of glycogen (a polymer of glucose), myoglobin, a red-colored protein necessary for binding oxygen molecules that diffuse into muscle fibers, and mitochondria.
In neuromuscular disease, a variety of factors can influence the compositional and micro structural aspects of muscle, including most notably muscle fiber atrophy and disorganization, the deposition of fat and connective tissues, as occurs in muscular dystrophy, and the presence of inflammation, among many other pathologies. EIM captures these ...
Each muscle fiber contains sarcolemma, sarcoplasm, and sarcoplasmic reticulum. The functional unit of a muscle fiber is called a sarcomere. [2] Each muscle cell contains myofibrils composed of actin and myosin myofilaments repeated as a sarcomere. [3] Many nuclei are present in each muscle cell placed at regular intervals beneath the sarcolemma.
Single fiber electromyography assesses the delay between the contractions of individual muscle fibers within a motor unit and is a sensitive test for dysfunction of the neuromuscular junction caused by drugs, poisons, or diseases such as myasthenia gravis.
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The muscle fibers belonging to one motor unit can be spread throughout part, or most of the entire muscle, depending on the number of fibers and size of the muscle. [2] [3] When a motor neuron is activated, all of the muscle fibers innervated by the motor neuron are stimulated and contract. The activation of one motor neuron will result in a ...