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Myasthenia gravis (MG) is a long-term neuromuscular junction disease that leads to varying degrees of skeletal muscle weakness. [1] The most commonly affected muscles are those of the eyes, face, and swallowing. [1][5] It can result in double vision, drooping eyelids, and difficulties in talking and walking. [1]
Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [10][11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [12] Classic symptoms include thirst, polyuria ...
The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
A fasting blood sugar level of ≥ 7.0 mmol / L (126 mg/dL) is used in the general diagnosis of diabetes. [17] There are no clear guidelines for the diagnosis of LADA, but the criteria often used are that the patient should develop the disease in adulthood, not need insulin treatment for the first 6 months after diagnosis and have autoantibodies in the blood.
Myasthenia gravis is caused by autoantibodies to the postsynaptic acetylcholine receptors. Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder characterized by muscle weakness of the limbs. It is also known as myasthenic syndrome, Eaton–Lambert syndrome, and when related to cancer, carcinomatous myopathy.
Transient neonatal myasthenia gravis is a very rare condition in which a mother with myasthenia gravis passes down her myasthenia gravis-inducing antibodies to her fetus through the placenta, causing the fetus to be born with antibodies that attach to self-antigens at the neuromuscular junction.(reference 12) Most cases of transient neonatal ...
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