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Leukocytosis is a condition in which the white cell count is above the normal range in the blood. [ 1 ] [ 2 ] It is frequently a sign of an inflammatory response , [ 3 ] most commonly the result of infection , but may also occur following certain parasitic infections or bone tumors as well as leukemia .
An excess of white blood cells is usually due to infection or inflammation. Less commonly, a high white blood cell count could indicate certain blood cancers or bone marrow disorders. The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important subset of the complete blood count.
Left shift (medicine) Neutrophilic band cell. Left shift or blood shift is an increase in the number of immature cell types among the blood cells in a sample of blood. Many (perhaps most) clinical mentions of left shift refer to the white blood cell lineage, particularly neutrophil -precursor band cells, [1]: 84–84 thus signifying bandemia.
Neutrophilia. Neutrophilia (also called neutrophil leukocytosis or occasionally neutrocytosis) is leukocytosis of neutrophils, that is, a high number of neutrophils in the blood. [1] Because neutrophils are the main type of granulocytes, mentions of granulocytosis often overlap in meaning with neutrophilia.
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
Symptomatic Hyperleukocytosis (Leukostasis) is defined by a tremendously high blast cell count along with symptoms of decreased tissue perfusion. Leukostasis is associated with people who have bone and blood disorders and is very common among people with acute myeloid leukemia or chronic myeloid leukemia. Leukostasis is a pathologic diagnosis ...
Conventionally, a leukocytosis exceeding 50,000 WBC/mm 3 with a significant increase in early neutrophil precursors is referred to as a leukemoid reaction. [2] The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature neutrophil precursors, in contrast to the immature forms typically seen in acute leukemia.
Toxic vacuolization. A vacuolated neutrophil. Specialty. Hematology. Causes. Sepsis, bacterial infection, alcohol toxicity, liver failure, G-CSF treatment. Toxic vacuolation, also known as toxic vacuolization, [1] is the formation of vacuoles in the cytoplasm of neutrophils in response to severe infections or inflammatory conditions. [2][3]