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  2. IGF-1 LR3 - Wikipedia

    en.wikipedia.org/wiki/IGF-1_LR3

    Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). [1] [2] It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN ...

  3. Insulin-like growth factor 1 receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor...

    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF ...

  4. Insulin-like growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_1

    Insulin-like growth factor 1. Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. [5] In the 1950s IGF-1 was called " sulfation factor" because it stimulated sulfation of cartilage in vitro ...

  5. Gilead gets US FDA approval for inflammatory liver disease drug

    www.aol.com/news/us-fda-approves-gileads-liver...

    (Reuters) -The U.S. Food and Drug Administration on Wednesday approved Gilead Sciences' liver disease treatment, Livdelzi, which it gained through a $4.3 billion buyout of CymaBay Therapeutics ...

  6. Insulin-like growth factor-binding protein - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor...

    IGFBP-3, the most abundant protein, accounts for 80% of all IGF binding. IGF-1 binds to IGFBP-3 in a 1:1 molar ratio. IGF-BP also binds to IGF-1 inside the liver, allowing growth hormone to continuously act upon the liver to produce more IGF-1. IGF binding proteins (IGFBPs) are proteins of 24 to 45 kDa. All six IGFBPs share 50% homology with ...

  7. Insulin-like growth factor 2 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_2

    Insulin-like growth factor II E-peptide (somatomedians-A ) Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood.

  8. Where to shop today's best sales: Get an iPad for under $200 ...

    www.aol.com/lifestyle/where-to-shop-todays-best...

    J.Crew: Get up to 40% off sitewide. Kate Spade Outlet: Get up to 70% off 350-plus styles, plus an extra 20% off with code SUMMER20. Madewell: Grab some of the brand's biggest bestsellers for as ...

  9. Mecasermin - Wikipedia

    en.wikipedia.org/wiki/Mecasermin

    Mecasermin, sold under the brand name Increlex, also known as recombinant human insulin-like growth factor-1 (rhIGF-1), is a recombinant form of human insulin-like growth factor 1 (IGF-I) which is used in the long-term treatment of growth failure and short stature in children with severe primary IGF-I deficiency, for instance due to growth hormone deficiency or Laron syndrome (growth hormone ...

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