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Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. [ 10 ] Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever.
History of aspirin. Aspirin (acetylsalicylic acid), an organic compound that does not occur in nature, was first synthesised in 1899. In 1897, scientists at the drug and dye firm Bayer began investigating acetylated organic compounds as possible new medicines, following the success of acetanilide ten years earlier.
Mechanism of action of aspirin. Tridimensional model of the chemical structure of aspirin. Aspirin causes several different effects in the body, mainly the reduction of inflammation, analgesia (relief of pain), the prevention of clotting, and the reduction of fever. Much of this is believed to be due to decreased production of prostaglandins ...
“While ibuprofen, acetaminophen and aspirin are often considered interchangeable, each has its ingredient makeup and intended purpose,” Dr. Brynna Connor, a family medicine physician and ...
Alka-Seltzer is an effervescent antacid and pain reliever owned by Bayer since 1978. First marketed by the Dr. Miles Medicine Company of Elkhart, Indiana, United States, Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid) (ASA), sodium bicarbonate, and anhydrous citric acid. [1] The aspirin is a pain reliever and anti ...
Salicylic acid is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport. [53] Salicylic acid is involved in endogenous signaling, mediating plant defense against pathogens. [54]
Active ingredients that have been commonly used in compound analgesics include: aspirin or ibuprofen. caffeine. codeine or oxycodone. paracetamol (acetaminophen) phenacetin. There is evidence that a compound of two analgesics with different mechanism of action can have an increased painkilling effect over the sum of the effect of each ...
Aspirin/paracetamol/caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. [1] It contains aspirin , a non-steroidal anti-inflammatory drug ; paracetamol (acetaminophen), an analgesic ; and caffeine , a stimulant .