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Direct alcohol tolerance is largely dependent on body size. Large-bodied people will require more alcohol to reach insobriety than lightly built people. [4] The alcohol tolerance is also connected with activity of alcohol dehydrogenases (a group of enzymes responsible for the breakdown of alcohol) in the liver, and in the bloodstream.
The relationship between alcohol consumption and body weight is the subject of inconclusive studies. Findings of these studies range from increase in body weight to a small decrease among women who begin consuming alcohol. [1] [2] Some of these studies are conducted with numerous subjects; one involved nearly 8,000 and another 140,000 subjects.
Alcohol (also known as ethanol) has a number of effects on health. Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1]
The initial buzz and immediate effects of alcohol may be familiar. Here’s how the long-term consequences of excessive drinking can gradually take a toll on your health. 1.
In Osborn’s neurosurgery practice, he has seen firsthand the effects of alcohol on the brain. "We know that people who drink have bad brains," he said. "I actually operated on one two days ago."
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