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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    A number of health problems may develop, such as attacks of pain (known as a sickle cell crisis) in joints, anemia, swelling in the hands and feet, bacterial infections, dizziness [9] and stroke. [1] Long-term pain may develop as people get older. [2] The average life expectancy in the developed world is 40 to 60 years. It often gets worse with ...

  3. Crizanlizumab - Wikipedia

    en.wikipedia.org/wiki/Crizanlizumab

    146 232.04 g·mol −1. Crizanlizumab, sold under the brand name Adakveo among others, is a monoclonal antibody medication that binds to P-selectin. [3] It is a medication used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. [3][4][6] It is given by injection into a vein. [3][4 ...

  4. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...

  5. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    Neuropathic pain, hyperalgesia, osteomyelitis. A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1][2] It is a form of sickle cell crisis. Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of ...

  6. For people with sickle cell disease, ERs can mean life ... - AOL

    www.aol.com/news/people-sickle-cell-disease-ers...

    A sickle cell health crisis can escalate into life-threatening complications, but patients still struggle to get seen quickly in emergency rooms and also to get pain medicine.

  7. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    The crisis is a common complication in sickle-cell patients and can be associated with one or more symptoms including fever, cough, excruciating pain, sputum production, shortness of breath, or low oxygen levels. [2]

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