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  2. α-Linolenic acid - Wikipedia

    en.wikipedia.org/wiki/Α-Linolenic_acid

    Because the efficacy of n−3 long-chain polyunsaturated fatty acid (LC-PUFA) synthesis decreases down the cascade of α-linolenic acid conversion, DHA synthesis from α-linolenic acid is even more restricted than that of EPA. [14] Conversion of ALA to DHA is higher in women than in men. [15]

  3. Eicosapentaenoic acid - Wikipedia

    en.wikipedia.org/wiki/Eicosapentaenoic_acid

    The human body converts a portion of absorbed alpha-linolenic acid (ALA) to EPA. ALA is itself an essential fatty acid, and humans need an appropriate supply of it. The efficiency of the conversion of ALA to EPA, however, is much lower than the absorption of EPA from food containing it.

  4. Omega-3 fatty acid - Wikipedia

    en.wikipedia.org/wiki/Omega-3_fatty_acid

    The conversion of ALA to EPA and further to DHA in humans has been reported to be limited, but varies with individuals. [2] [34] Women have higher ALA-to-DHA conversion efficiency than men, which is presumed [35] to be due to the lower rate of use of dietary ALA for beta-oxidation. One preliminary study showed that EPA can be increased by ...

  5. Essential fatty acid - Wikipedia

    en.wikipedia.org/wiki/Essential_fatty_acid

    Some plant-based foods contain omega−3 in the form of alpha-linolenic acid (ALA), which appears to have a modest benefit for cardiovascular health. [23] The human body can (and in case of a purely vegetarian diet often must unless certain algae or supplements derived from them are consumed) convert ALA to EPA and subsequently DHA. This ...

  6. Essential fatty acid interactions - Wikipedia

    en.wikipedia.org/wiki/Essential_fatty_acid...

    Other dietary essential fatty acids are involved in inflammatory signalling and can oppose the impact of the arachidonic acid cascade. For example, EPA (20:5 ω-3) competes with AA and is ingested from oily fish, algae oil, or alpha-linolenic acid (derived from walnuts, hemp oil, and flax oil).

  7. Linoleoyl-CoA desaturase - Wikipedia

    en.wikipedia.org/wiki/Linoleoyl-CoA_desaturase

    In humans, it is used principally for the conversions of cis-linoleic acid to gamma-linolenic acid (GLA), and palmitic acid to sapienic acid. It also converts alpha-linolenic acid (ALA) to stearidonic acid and tetracosatetraenoic acid to tetracosapentaenoic acid, intermediate steps in the synthesis of ALA to EPA and of EPA to DHA, respectively.

  8. Fatty acid ratio in food - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_ratio_in_food

    It has been claimed that among hunter-gatherer populations, omega-6 fats and omega-3 fats are typically consumed in roughly a 1:1 ratio. [3] [4] [better source needed] At one extreme of the spectrum of hunter-gatherer diets, the Greenland Inuit, prior to the late Twentieth Century, consumed a diet in which omega-6s and omega-3s were consumed in a 1:2 ratio, thanks to a diet rich in cold-water ...

  9. List of unsaturated fatty acids - Wikipedia

    en.wikipedia.org/wiki/List_of_unsaturated_fatty...

    Eicosapentaenoic acid (EPA) has 20 carbons, is found in fish oil, is a pentaunsaturated fatty acid. It is one of the essential fatty acids . The recommendation of ingesting fish oil supplements during pregnancy is said to help increase the cognitive ability at 6 months, but mercury concentration in fish products offsets the effect.