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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Alcohol: Cannabis: Tincture of cannabis. Herb and Al. Judgement Day Cross fading, twisting, getting twisted [13] Called Judgement Day in Ghana when cannabis is added to the drink Alcohol: Cocaine: Snow-cone Snow-coning Ethanol is metabolized into cocaethylene [14] Alcohol: MDMA: Tipsy flip Tipsy flipping It may be dangerous Alcohol: Nicotine ...

  3. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    For example: Benzodiazepines can cause death when mixed with other CNS depressants such as opioids, alcohol, or barbiturates. [7] [8] [9] GHB combined with alcohol can lead to a long-lasting coma-like state (‘G-sleep’) or even accidental death, particularly in light of GHB's narrow threshold for overdose. Depressants combined with ...

  4. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Interactions with other drugs, food and drink, and other factors may increase or decrease the effect of certain analgesics and alter their half-life. Because some listed analgesics are prodrugs or have active metabolites, individual variation in liver enzymes (e.g., CYP2D6 enzyme) may result in significantly altered effects.

  5. Cross-tolerance - Wikipedia

    en.wikipedia.org/wiki/Cross-tolerance

    Cross-tolerance is a phenomenon that occurs when tolerance to the effects of a certain drug produces tolerance to another drug. It often happens between two drugs with similar functions or effects—for example, acting on the same cell receptor or affecting the transmission of certain neurotransmitters.

  6. List of Schedule II controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_II...

    This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. [1] The following findings are required, by section 202 of that Act, for substances to be placed in this schedule: The drug or other substance has a high potential for abuse.

  7. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Librium (chlordiazepoxide) – a benzodiazepine used to treat acute alcohol withdrawal; Lithobid, Eskalith – a mood stabilizer; Loxam (escitalopram) – an antidepressant of the SSRI class; Lunesta (eszopiclone) – a non-benzodiazepine hypnotic; Luvox (fluvoxamine) – an antidepressant of the SSRI class

  8. U.S. warns about fake, dangerous pills being sold in Mexico

    www.aol.com/news/us-warns-fake-dangerous-pills...

    A study led by researchers at the University of California, Los Angeles found that 68% of the 40 Mexican pharmacies visited in four northern Mexico cities sold Oxycodone, Xanax or Adderall, and ...

  9. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    In humans, N-demethylation of oxycodone to noroxycodone by CYP3A4 is the major metabolic pathway, accounting for 45% ± 21% of a dose of oxycodone, while O-demethylation of oxycodone into oxymorphone by CYP2D6 and 6-ketoreduction of oxycodone into 6-oxycodols represent relatively minor metabolic pathways, accounting for 11% ± 6% and 8% ± 6% ...