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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
Drenching Merino hoggets, Walcha, NSW U.S. soldiers treating animals with de-worming medication in Eswatini during VETCAP. Deworming (sometimes known as worming, drenching or dehelmintization) is the giving of an anthelmintic drug (a wormer, dewormer, or drench) to a human or animals to rid them of helminths parasites, such as roundworm, flukes and tapeworm.
In cattle, prevalence of anthelminthic resistance varied between anthelmintic classes from 0–100% (benzimidazoles and macrocyclic lactones), 0–17% (levamisole) and 0–73% (moxidectin), and both Cooperia and Ostertagia survived treatment. [14] However, resistance is not seen as often in the parasitic helminths that affect cattle, compared ...
Mature horses appear to develop a certain degree of resistance to this parasite, but it is a concern for younger horses up to about two years old. [4] P. equorum is one of the few parasites where a natural immunity develops in the host. [3] However, when an infection is found in an adult horse, both the worm and egg counts are substantially low ...
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
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