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The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs. The DDD enables comparison of drug usage between different drugs in ...
The dose values are divided by the maximum dose, referred to as d max, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber, since water is very similar to human tissue with regard to radiation scattering and absorption.
This included a proposal to discontinue use of equivalent dose as a separate protection quantity. This would avoid confusion between equivalent dose, effective dose and dose equivalent, and to use absorbed dose in Gy as a more appropriate quantity for limiting deterministic effects to the eye lens, skin, hands & feet. [10]
CDE is defined by the United States Nuclear Regulatory Commission in Title 10, Section 20.1003, of the Code of Federal Regulations (10 CFR 20.1003), such that "The Committed dose equivalent, CDE (H T,50) is the dose to some specific organ or tissue of reference (T) that will be received from an intake of radioactive material by an individual during the 50-year period following the intake".
The Deep-dose equivalent (DDE) is a measure of external radiation exposure defined by US regulations. It is reported alongside eye and shallow dose equivalents on typical US dosimetry reports. It represents the dose equivalent at a tissue depth of 1 cm (1000 mg/cm2) due to external whole-body exposure to ionizing radiation. [1]
Prescribed daily dose (PDD) is the usual dose of medication calculated by looking at a group of prescriptions for the medication in question. [1] At times the PDD needs to be related to the condition being treated .
Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...
The Total effective dose equivalent (TEDE) is a radiation dosimetry quantity defined by the US Nuclear Regulatory Commission to monitor and control human exposure to ionizing radiation. It is defined differently in the NRC regulations and NRC glossary.