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Genetic reassortment of several influenza A strains culminates in the emergence of a highly pathogenic H5N1 subtype bearing the clade 2.3.4.4b hemagglutinin (HA) gene. [ 13 ] [ 12 ] 2021
The highly pathogenic influenza A virus subtype H5N1 is an emerging avian influenza virus that is causing global concern as a potential pandemic threat. It is often referred to simply as "bird flu" or "avian influenza", even though it is only one of many subtypes.
Influenza A/H5N1 was first detected in 1959 after an outbreak of highly pathogenic avian influenza in Scotland, which infected two flocks of chickens. [59] [60] The next detection, and the earliest infection of humans by H5N1, was an epizootic (an epidemic in nonhumans) of H5N1 influenza in Hong Kong's poultry population in 1997. This outbreak ...
The threat of avian flu has dominated public health discourse as cases become increasingly more widespread and severe. H5N1, a highly pathogenic strain, was present in several continents as early ...
Highly pathogenic avian influenza in chickens, for example, impacts internal organs and has a 90-100% mortality rate in just 48 hours after infection, according to the CDC.
Some flu viruses carried by birds cause only mild infections and are classified as low-pathogenic viruses. In contrast, H5N1 often kills birds that catch it, so it is classified as a highly ...
While other H5N1 influenza strains are known, they are significantly different on a genetic level from a highly pathogenic, emergent strain of H5N1, which was able to achieve hitherto unprecedented global spread in 2008. [1] The H5N1 strain is a fast-mutating, highly pathogenic avian influenza virus (HPAI) found in multiple bird species. It is ...
Bird flu has been killing birds for decades. It began in February of 2022 when the U.S. Department of Agriculture detected the strain on a midwest poultry farm. "A finding of highly pathogenic ...