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  2. Timeline of the opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_the_opioid...

    1998 Purdue's audiotapes, brochures, videotapes, literature and its website "Partners Against Pain", "claimed that the risk of addiction from OxyContin was extremely small." [16] [10] Fentanyl. 2 mg (white powder to the right) is a lethal dose in most people. [17] US penny is 19 mm (0.75 in) wide. 1998 In November the FDA approved Actiq . [1]

  3. Opioid epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic_in_the...

    Heroin addiction began to make the news around 1970 when rock star Janis Joplin died from an overdose. During and after the Vietnam War, addicted soldiers returned from Vietnam, where heroin was easily bought. Heroin addiction grew within low-income housing projects during the same time period. [63]

  4. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    The state of Oklahoma argued that Purdue Pharma helped start the opioid epidemic because of assertive marketing and deceptive claims on the dangers of addiction. [41] One of the marketing strategies was to redefine "substance use disorder" as "pseudo addiction". [40]

  5. Evolutionary models of human drug use - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_models_of...

    The hijack model of substance addiction suggests that Psychoactive drugs act on ancient and evolutionarily conserved neural mechanisms associated with positive emotions that evolved to mediate incentive behavior. [1] [2] They induce emotions that in human evolutionary history signaled a benefit for the group. Modern drugs tap into these ...

  6. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    From the start, Wilson intended AA to work with, not against or instead of, the latest and best medical science to treat addiction. In 1965, he recruited Dr. Vincent Dole to become a member of AA’s board of trustees.

  7. History of United States drug prohibition - Wikipedia

    en.wikipedia.org/wiki/History_of_United_States...

    The rate of opiate addiction increased from about .72 addicts per 1,000 people to a high of 4.59 per 1,000 in the 1890s. [ 2 ] Efforts to regulate the sale of pharmaceuticals began around 1860, and laws were introduced on a state-to-state basis that created penalties for mislabeling drugs, adulterating them with undisclosed narcotics, and ...

  8. Macaulay Culkin addresses drug rumors: 'I was not ... - AOL

    www.aol.com/article/2016/07/18/macaulay-culkin...

    Macaulay Culkin is speaking out about the drug addiction rumors that have shadowed him for years. In a rare interview, the former child star tells The Guardian that the public was "not necessarily ...

  9. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Addiction is a neuropsychological disorder characterized by a persistent and ... these stimuli start to function ... The cultural model did face criticism by ...