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His postdoctoral research was at the laboratory of Rosalind Pitt-Rivers at the British National Institute for Medical Research where they co-discovered the active form of thyroid hormone, Triiodothyronine (T3). [2] In 1952, Gross began teaching at the SUNY Downstate Medical School, where he became a full professor in 1956.
Thyroid follicular cells (also called thyroid epithelial cells or thyrocytes [1]) are the major cell type in the thyroid gland, and are responsible for the production and secretion of the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3).
Triiodothyronine, also known as T 3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. [1] Production of T 3 and its prohormone thyroxine (T 4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior ...
Triiodothyronine (T 3) and thyroxine (T 4) can be measured as free T 3 and free T 4, which are indicators of their activities in the body. [74] They can also be measured as total T 3 and total T 4, which depend on the amount that is bound to thyroxine-binding globulin (TBG). [74]
Liothyronine is a manufactured form of the thyroid hormone triiodothyronine (T 3). [2] It is most commonly used to treat hypothyroidism and myxedema coma. [2] It can be taken by mouth or by injection into a vein. [2] Side effects may occur from excessive doses. [2]
Total triiodothyronine (Total T 3) is rarely measured, having been largely superseded by free T3 tests. Total T3 is generally elevated in hyperthyroidism and decreased in hypothyroidism. [2] Reference ranges depend on the method of analysis. Results should always be interpreted using the range from the laboratory that performed the test.
The pituitary gland secretes thyrotropin (TSH; Thyroid Stimulating Hormone) that stimulates the thyroid to secrete thyroxine (T4) and, to a lesser degree, triiodothyronine (T3). The major portion of T3, however, is produced in peripheral organs, e.g. liver, adipose tissue, glia and skeletal muscle by deiodination from
Print/export Download as PDF ... It is formed from the breakdown of triiodothyronine. Levels can be affected in certain disease states. ... Synthesis of T 2 from T 3 ...