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Alzheimer's disease is related to semantic dementia, which both have similar symptoms. The main difference between the two being that Alzheimer's is categorized by atrophy to both sides of the brain while semantic dementia is categorized by loss of brain tissue in the front portion of the left temporal lobe. [ 16 ]
Other times, semantic paraphasias can result in empty speech, or the use of overly generic words such as "thing" or "stuff" to stand in for the word they cannot come up with. This leads to speech that contains real words but lacks any substantial meaning. Circumlocution: talking around the target word. [2]
It is suspected that an atypical form of Alzheimer's disease is the most common cause of logopenic progressive aphasia. [3] [4] Although patients with the logopenic variant of PPA are still able to produce speech, their speech rate may be significantly slowed due to word retrieval difficulty. [4]
Researchers have developed an AI tool that can predict with nearly 80% accuracy whether someone is at risk for developing Alzheimer’s disease based on their speech patterns.
A third variant of primary progressive aphasia, LPA was then added, [15] and is an atypical form of Alzheimer's disease. For PNFA, the core criteria for diagnosis include agrammatism and slow and labored speech. Inconsistent speech sound errors are also very common, including distortions, deletions, and insertions.
Aphasia, also known as dysphasia, [a] is an impairment in a person’s ability to comprehend or formulate language because of damage to specific brain regions. [2] The major causes are stroke and head trauma; prevalence is hard to determine, but aphasia due to stroke is estimated to be 0.1–0.4% in developed countries. [3]