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Phosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15% of the phospholipids in the human cerebral cortex. [7] In the plasma membrane, PS is localized exclusively in the cytoplasmic leaflet where it forms part of protein docking sites necessary for the activation of several key signaling pathways.
Visual symptoms including loss of vision or double vision; Speech symptoms including dysphonia (whispering speech), slurred or stuttering speech; Sensory disturbance including hemisensory syndrome (altered sensation down one side of the body) Numbness or inability to sense touch; Dizziness and balance problems; Pain (including chronic migraines)
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
[4] [6] [8] [11] Dr. Daniel LaChance, a physician at both the Austin Medical Center and the Mayo Clinic in nearby Rochester, Minnesota, was notified. He launched a request to area physicians to refer other patients with similar symptoms to him. [11] The Minnesota Department of Health was notified and began an investigation into the "outbreak."
Symptoms of cerebral infarction can help determine which parts of the brain are affected. If the infarct is located in the primary motor cortex , contralateral hemiparesis is said to occur. With brainstem localization, brainstem syndromes are typical: Wallenberg's syndrome , Weber's syndrome , Millard–Gubler syndrome , Benedikt syndrome or ...
Treatment is supportive and focused on improving symptoms: Dystonia is a common debilitating symptom and can be managed with oral medications, and sometimes with deep-brain electrical stimulation, therapy support for walking, eating, and manual tasks is essential. Later, in many of the diseases, slowing and stopping of movement (known as ...