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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine is sometimes considered the strongest weight loss prescription pill in terms of potency, but it’s usually recommended for short-term use. Phentermine-topiramate might work better, as ...
Phentermine was not shown to have harmful effects. [1] Fenfluramine acts as a serotonin releasing agent, [2] phentermine as primarily a norepinephrine releasing agent. Phentermine also induces the release of serotonin and dopamine, although to a far lesser extent than it induces the release of norepinephrine. [3]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
Phentermine-topiramate. This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate. Phentermine-topiramate is effective for weight loss and seems ...
If you take Qsymia, the starting dose is 3.75mg of phentermine and 23mg of topiramate daily for 14 days. The dose then increases to 7.5mg of phentermine and 46mg of topiramate daily for 90 days.