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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [11] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [11] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [11]
[5] [19] [21] [10] [22] [23] It is specifically used following treatment with or in combination with nitroimidazoles like metronidazole for recurrent bacterial vaginosis. [ 5 ] [ 22 ] [ 10 ] Although it has been reported to be effective and is widely used for this purpose, clinical studies of boric acid for treatment of bacterial vaginosis are ...
Bacterial vaginosis: The most commonly used antibiotics are metronidazole, available in both pill and gel form, and clindamycin available in both pill and cream form. [11] Yeast infections: Local azole, in the form of ovula and cream. All agents appear to be equally effective. [33]
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Formulation methods include vaginal tablets, vaginal cream, vaginal gel, [4] [medical citation needed] vaginal suppository and vaginal ring. It is used as an administration method for issues related to women's health, such as contraception. [ 5 ]
Bacterial vaginosis (BV) is an infection of the vagina caused by excessive growth of bacteria. [ 6 ] [ 12 ] Common symptoms include increased vaginal discharge that often smells like fish. [ 2 ] The discharge is usually white or gray in color. [ 2 ]