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V. cholerae is a highly motile, comma shaped, gram-negative rod. The active movement of V. cholerae inspired the genus name because "vibrio" in Latin means "to quiver". [29] Except for V. cholerae and V. mimicus, all other vibrio species are halophilic. Initial isolates are slightly curved, whereas they can appear as straight rods upon ...
Cholera autoinducer-1 (CAI-1) is an autoinducer signaling molecule present in the bacterium Vibrio cholerae, which causes cholera. CAI-1 is known structurally as a (S)-3-hydroxytridecan and regulates expression of virulence factors.
Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is an AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae. [1] [2] CTX is responsible for the massive, watery diarrhea characteristic of cholera infection. [3] It is a member of the heat-labile enterotoxin family.
Cholera is caused by ingesting a bacteria known as Vibrio cholerae. It's found in contaminated water and food, explains Ivers, which then produces a toxin in the small intestine that leads to the ...
In Vibrio cholerae T6SS studies, it has been observed that serotype O37 has high vas gene expression. Serotypes O139 and O1 on the other hand exhibit the opposite, with markedly low vas gene expression. It has been suggested that the differences in expression are attributable to differences in quorum-sensing levels.
In Vibrio cholerae the martx gene encodes six proteins: the MARTX toxin (RtxA), an acyltransferase (RtxC), a membrane fusion protein (RtxD), two ABC-transporters (RtxB and RtxE), and one protein with unknown function. [3] RtxA is a virulence factor involved in cholera which facilitates colonization of V. cholerae the small intestine
CTXφ is generally present and integrated into the genome of the V. cholerae bacterium, and more rarely in a virion from outside the bacterium. While integrated into the bacterial genome, CTX prophages are found on each of the two chromosomes (in the O1 serogroup of V. cholerae) or arranged in tandem on the larger chromosome (in the El Tor biotype of V. cholerae). [2]
Cholera (/ ˈ k ɒ l ər ə /) is an infection of the small intestine by some strains of the bacterium Vibrio cholerae. [4] [3] Symptoms may range from none, to mild, to severe. [3]The classic symptom is large amounts of watery diarrhea lasting a few days. [2]