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Palmitoyl pentapeptide-4 (palmitoyl pentapeptide-3 before 2006) is a matrikine used in anti-wrinkle cosmetics. It was launched in 2000 as an active ingredient for the personal care industry under the trade name Matrixyl by the Spanish cosmetic active ingredient manufacturer Sederma SAS.
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StriVectin Hyaluronic Tripeptide Gel-Cream for Eyes (2-pack) $40 at Costco. La Mer Creme De La Mer Moisturizing Cream (2 oz) ... wrinkles, crow's feet and puffiness. $40 at Costco. 3. La Mer Creme ...
To choose the best eye cream for wrinkles and fine lines, ingredients are key. Here, dermatologists explain what to look for in an anti-aging eye cream, and the best products for every budget.
Acetyl hexapeptide-8 or acetyl hexapeptide-8 amide (some sources incorrectly refer to this peptide as acetyl hexapeptide-3) is a synthetic anti-wrinkle cosmetics ingredient. It is a peptide which is a fragment of SNAP-25, a substrate of botulinum toxin (Botox). Acetyl hexapeptide-8 is marketed as Argireline® peptide by Lubrizol. [1]
A main target of PEA is proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α). [3] [4] PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119. [5] PEA cannot strictly be considered a classic endocannabinoid because it lacks affinity for the cannabinoid receptors CB1 and CB2. [6]