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In the case of copper the adult UL is set at 10 mg/day. [4] Copper gluconate is sold as a dietary supplement to provide copper. The typical dose is 2.0 mg copper per day. This is one-fifth what the IOM considers a safe upper limit. Long-term intake at amounts higher than the UL may cause liver damage. [4]
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Dose range Approximate daily intakes Health outcomes Death Gross dysfunction and disturbance of metabolism of other nutrients; hepatic "detoxification" and homeostasis overwhelmed Toxic >5.0 mg/kg body weight: Gastrointestinal metallothionein induced (possible differing effects of acute and chronic exposure) 100 μg/kg body weight
Copper toxicity (or Copperiedus) is a type of metal poisoning caused by an excess of copper in the body. Copperiedus could occur from consuming excess copper salts, but most commonly it is the result of the genetic condition Wilson's disease and Menke's disease, which are associated with mismanaged transport and storage of copper ions.