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Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]
However, the long-term benefit is greater in those with grade III hemorrhoids as compared to rubber band ligation. [45] It is the recommended treatment in those with a thrombosed external hemorrhoid if carried out within 24–72 hours. [6] [16] Evidence to support this is weak, however. [28]
However, some hemorrhoids will not respond to topical anti-inflammatory suppositories and creams and may need additional therapy including the application of thermal therapies, a rubber-band ...
Hemorrhoids are fed by arteries and drained by veins. The arterial blood supply is based on the superior rectal (hemorrhoidal) artery. Just as veins in the leg weaken and become prominent, hemorrhoidal veins also may become varicose, resulting in internal hemorrhoids or “piles”. Internal hemorrhoids are divided into four grades.
Perianal hematoma are caused by the rupture of a small vein that drains blood from the anus. [4] This rupture may be the result of forceful or strained bowel movement, anal sex or caused by heavy lifting, coughing or straining.
Intravitreal injection was first mentioned in a study in 1911, in which the injection of air was used to repair a detached retina. [6] [7] [8] There were also investigations evaluating intravitreal antibiotics injection using sulfanilamide and penicillin to treat endophthalmitis in the 1940s, yet due to the inconsistency of results and safety concerns, this form of drug delivery was only for ...
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