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Degenerative disc disease; Other names: Degenerative disc disorder, intervertebral disc degeneration: Degenerated disc between C5 and C6 (vertebra at the top of the picture is C2), with osteophytes anteriorly (to the left) on the lower portion of the C5 and upper portion of the C6 vertebral body. Specialty: Orthopedics: Risk factors: Connective ...
Degenerative changes cause compression of the spinal cord. Degenerative disc disease (DDD) may trigger the pathogenesis of neurogenic claudication. [17] When intervertebral discs degenerate and change shape in DDD, the normal movements of the spine are interrupted.
Degenerative disc disease occurs over time when the discs within each vertebra in the neck begin to fall apart and begin to disintegrate. Because each vertebra can cause pain in different areas of the body, the pain from the disease can be sensed in the back, leg, neck area, or even the arms.
Degenerative disc disease causes narrowing of the spaces. [27] Facet joints break down; Facet joints may hypertrophy [28] Compression fractures of the spine, which are common in osteoporosis [29] Synovial cysts form on the facet joints causing compression of the spinal sac of nerves (thecal sac)
A research group led by Gilligan has presented a description of how they hypothesize 4 stages, from infection of the discus to developing Modic changes in the vertebrae. [ 57 ] The first study to investigate the efficacy of long-term antibiotic treatment for patients with Modic changes was published in 2013. [ 58 ]
The natural evolution of disc disease and degeneration leads to stiffening of the intervertebral joint. This leads to osteophyte formation—a bony overgrowth about the joint. This process is called spondylosis, and is part of the normal aging of the spine. This has been seen in studies of normal and diseased spines.
Some authors favour degeneration of the intervertebral disc as the major cause of spinal disc herniation and cite trauma as a minor cause. [7] Disc degeneration occurs both in degenerative disc disease and aging. [8] With degeneration, the disc components – the nucleus pulposus and annulus fibrosus – become exposed to altered loads ...
1. a herniated disc when other non-surgical treatments have failed. The nucleus pulposus (the jelly-like center of the disc) of the herniated disc bulges out through the annulus (surrounding wall) and presses on the nerve root next to it. 2. degenerative disc disease (spondylosis). The disc consists of about 80% water.
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