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The sulfacetamide inhibits the growth of the bacterium Cutibacterium acnes that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores. [3] In 2022, it was the 300th most commonly prescribed medication in the United States, with more than 300,000 prescriptions. [4] [5]
Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. [4] When combined with sulfur , it is sold under the brand names Plexion , Clenia, Prascion, and Avar, which contain 10% sulfacetamide and 5% sulfur.
Organic sulfur content ≥ 5.5%, ammonium content ≥ 2.5%. — Chinese definition according to ChP 10 [12] As a result, Chinese "ichthammol" is very different from standard ichthammol. The characteristic bitumen-like odor (originating from the bituminous source material) is missing with Chinese material. [13]
Salicylic acid is an organic compound with the formula HOC 6 H 4 COOH. [3] A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin). [3]
Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. [5] Specific condition with hyperkeratosis where urea cream is useful include: Dry skin and rough skin [5] Dermatitis [5]
Calamine is a combination of zinc oxide and 0.5% ferric oxide (Fe 2 O 3). [6] The lotion is produced with additional ingredients such as phenol and calcium hydroxide. [6] [7] The use of calamine lotion dates back as far as 1500 BC. [8] It is on the World Health Organization's List of Essential Medicines. [9]