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  2. Clinodactyly - Wikipedia

    en.wikipedia.org/wiki/Clinodactyly

    Clinodactyly is an autosomal dominant trait that has variable expressiveness and incomplete penetrance. [citation needed] Clinodactyly can be passed through inheritance and presents as either an isolated anomaly or a component manifestation of a genetic syndrome. [2] Many syndromes are associated with clinodactyly, including those listed below.

  3. Tethered cord syndrome - Wikipedia

    en.wikipedia.org/wiki/Tethered_cord_syndrome

    This can lead to additional loss of movement or feeling, or the onset of pain or autonomic nervous system symptoms. [6] In adults, onset of symptoms typically include: Severe pain (in the lower back and radiating into the legs, groin, and perineum) Bilateral muscle weakness and numbness; Loss of feeling and movement in lower extremities

  4. Cornelia de Lange syndrome - Wikipedia

    en.wikipedia.org/wiki/Cornelia_de_Lange_Syndrome

    If pain or a medical issue is the cause, once treated, the behaviour diminishes. There is evidence for some features of premature aging including the early development of Barrett's esophagus , osteoporosis present in the teenage years, premature greying of hair and some changes to the skin of the face causing a more aged appearance compared to ...

  5. Syringomyelia - Wikipedia

    en.wikipedia.org/wiki/Syringomyelia

    The damage may result in loss of feeling, paralysis, weakness, [4] and stiffness in the back, shoulders, and extremities. Syringomyelia may also cause a loss of the ability to feel extremes of hot or cold, especially in the hands. It may also lead to a cape-like bilateral loss of pain and temperature sensation along the upper chest and arms.

  6. Neurogenic bowel dysfunction - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_bowel_dysfunction

    Bowel dysfunction caused by a spinal cord injury will vary greatly depending on the severity and level of the spinal cord lesion. In complete spinal cord injury both sensory and motor functions are completely lost below the level of the lesion so there is a loss of voluntary control and loss of sensation of the need to defecate. [12]

  7. Periodic paralysis - Wikipedia

    en.wikipedia.org/wiki/Periodic_paralysis

    Potassium levels may be low, high, or normal during attacks of ATS. Patients with ATS may also have skeletal abnormalities like scoliosis (curvature of the spine), webbing between the second and third toes or fingers , crooked fingers (clinodactyly), a small jaw (micrognathia) and low-set ears. Patients need to have another form of periodic ...

  8. Diffuse noxious inhibitory control - Wikipedia

    en.wikipedia.org/wiki/Diffuse_noxious_inhibitory...

    Noxious stimuli activate the endings of nociceptive C and A delta nerve fibers, which carry the signal to neurons in the dorsal horn of spinal cord. DNIC refers to the mechanism by which dorsal horn wide dynamic range neurons responsive to stimulation from one location of the body may be inhibited by noxious stimuli (such as heat, high pressure or electric stimulation) applied to another ...

  9. Primary ciliary dyskinesia - Wikipedia

    en.wikipedia.org/wiki/Primary_ciliary_dyskinesia

    Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive genetic ciliopathy, that causes defects in the action of cilia lining the upper and lower respiratory tract, sinuses, Eustachian tube, middle ear, fallopian tube, and flagella of sperm cells. The alternative name of "immotile ciliary syndrome" is no longer favored as the cilia do ...

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