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  2. Antiemetic - Wikipedia

    en.wikipedia.org/wiki/Antiemetic

    An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]

  3. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    5-HT 3 receptor antagonists or serotonin antagonists were first introduced in the early 1990s, and they have become the most widely used antiemetic drugs in chemotherapy. [29] They have also been proven safe and effective for treatment of postoperative nausea and vomiting. [30]

  4. Vomiting - Wikipedia

    en.wikipedia.org/wiki/Vomiting

    Antiemetics act by inhibiting the receptor sites associated with emesis. Hence, anticholinergics, antihistamines, dopamine antagonists, serotonin antagonists, and cannabinoids are used as antiemetics. [36] Evidence to support the use of antiemetics for nausea and vomiting among adults in the emergency department is poor. [37]

  5. NK1 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/NK1_receptor_antagonist

    It was developed up to phase II clinical trials for the treatment of postoperative nausea and vomiting, migraine and motion sickness. It showed good results in emesis, but development was discontinued. [12] LY-303870, or lanepitant (figure 5), is an N-acetylated reduced amide of L-tryptophan that was discovered by Eli Lilly. It underwent phase ...

  6. Droperidol - Wikipedia

    en.wikipedia.org/wiki/Droperidol

    It has a central antiemetic action and effectively prevents postoperative nausea and vomiting in adults using doses as low as 0.625 mg. . For treatment of nausea and vomiting, droperidol and ondansetron are equally effective; droperidol is more effective than metoclopramide. [8]

  7. Postoperative nausea and vomiting - Wikipedia

    en.wikipedia.org/wiki/Postoperative_nausea_and...

    Nausea and vomiting can be extremely distressing for patients, and so is one of their major concerns. [10] Vomiting has been associated with major complications, such as pulmonary aspiration of gastric content, and might endanger surgical outcomes after certain procedures, for example after maxillofacial surgery with wired jaws.

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