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A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. [ 1 ] [ 2 ] [ 3 ] Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer.
When examining cytologic specimens, a diagnosis of ASC-US is given if squamous cells are suspicious for low-grade squamous intraepithelial lesion (LSIL) but do not fulfill the criteria. This may be due to limitations in the quality of the specimen, or because the abnormalities in the cells are milder than that seen in LSIL. [ 6 ]
LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
Because of this, LSIL results can be managed with a simple "watch and wait" philosophy. However, because there is a 12–16% chance of progression to more severe dysplasia, the physician may want to follow the results more aggressively by performing a colposcopy with biopsy . [ 7 ]
Medical imaging is then done to determine whether or not the cancer has spread. [2] HPV vaccination is the most cost-effective public health measure against cervical cancer. [14] There are six licensed HPV vaccines. [16] They protect against two to seven high-risk strains of this family of viruses and may prevent up to 90% of cervical cancers.
local medical doctor: LMP: last menstrual period—first day of the menstrual period low malignant potential LMWH: low-molecular-weight heparin: LN: lymph node Logical Observation Identifiers Names and Codes (LOINC) LND: lymph node dissection: LNG: levonorgestrel: LNI: lymph node involvement: LOA: left occipitoanterior (fetal position) level of ...
Dysplasia is the earliest form of precancerous lesion which pathologists can recognize in a pap smear or in a biopsy. Dysplasia can be low grade or high grade. The risk of low-grade dysplasia transforming into high-grade dysplasia, and eventually cancer, is low. Treatment is usually straightforward.
Anal dysplasia is a pre-cancerous condition which occurs when the lining of the anal canal undergoes abnormal changes. It can be classified as low grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL). [1] Most cases are not associated with symptoms, but people may notice lumps in and around the ...