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A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. [ 1 ] [ 2 ] [ 3 ] Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer.
When examining cytologic specimens, a diagnosis of ASC-US is given if squamous cells are suspicious for low-grade squamous intraepithelial lesion (LSIL) but do not fulfill the criteria. This may be due to limitations in the quality of the specimen, or because the abnormalities in the cells are milder than that seen in LSIL. [ 6 ]
Precancerous cells (cervical intraepithelial neoplasia) that would lead to cancer and early-stage cervical cancer (IA1) can be treated effectively by various surgical techniques. Surgical treatment methods include excision, where a cone-shaped portion of the cervix is removed, and ablation which removes only the parts with abnormal tissues.
LSIL: low-grade squamous intraepithelial lesion: LST: laterally spreading tumor: LR: lactated Ringer's solution: LRINEC: Laboratory Risk Indicator for Necrotizing Soft Tissue Infections Score LRTI: lower respiratory tract infection: LT: heat-labile enterotoxin: LTAC: long-term acute care: LTCS: low transverse cesarean section: LUL: left upper ...
Dysplasia is the earliest form of precancerous lesion recognizable in a biopsy. Dysplasia can be low-grade or high-grade. High-grade dysplasia may also be referred to as carcinoma in situ. Invasive carcinoma, usually simply called cancer, has the potential to invade and spread to surrounding tissues and structures, and may eventually be lethal.
Anal dysplasia is a pre-cancerous condition which occurs when the lining of the anal canal undergoes abnormal changes. It can be classified as low grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL). [1] Most cases are not associated with symptoms, but people may notice lumps in and around the ...
Because of this, LSIL results can be managed with a simple "watch and wait" philosophy. However, because there is a 12–16% chance of progression to more severe dysplasia, the physician may want to follow the results more aggressively by performing a colposcopy with biopsy . [ 7 ]
CLL is commonly preceded by a pre-cancerous state known as monoclonal B-cell lymphocytosis (MBL). [33] This occurs when there is in an increase in a specific type of white blood cells but the number remains less than 5 billion cells per liter (L) (5x10 9 /L) of blood. [ 33 ]