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Testicular cancer is highly treatable and usually curable. [5] Treatment options may include surgery, radiation therapy, chemotherapy, or stem cell transplantation. [2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%. [4] Globally testicular cancer affected about 686,000 people in 2015. [6]
Leydig cell tumour, also Leydig cell tumor (US spelling), (testicular) interstitial cell tumour and (testicular) interstitial cell tumor (US spelling), is a member of the sex cord-stromal tumour group [2] of ovarian and testicular cancers. It arises from Leydig cells. While the tumour can occur at any age, it occurs most often in young adults.
The body has a central vessel surrounded by fibrous tissue, called the fibrovascular core, and it is surrounded by layers of the tumoral cells at the surface of that stalk. The structure is located in open cystic space also lined by tumoral cells. All those structures together are called a Schiller–Duval body and resemble primitive glomerulus.
Symptoms of testicular cancer can include a bump on a testicle or a swollen testicle, according to the American Cancer Society. Often, signs do not develop until the cancer is more advanced, the ...
It is the most common testicular cancer of non-germ cell origin. [13] Sonography may be used to identify cystic areas, but it is unable to tell benign tumours apart from malignant tumours. [13] Adrenomyeloneuropathy is another example of a disease affecting the Leydig cell. [14]
Cell/tissue normal location Ovary (female) Testicle (male) Mixed Cell/tissue type Sex cord: Granulosa cell tumour: Sertoli cell tumour: Gynandroblastoma Gonadal stroma: Thecoma, Fibroma: Leydig cell tumour: Gynandroblastoma Mixed Sertoli–Leydig cell tumour: Gynandroblastoma
PT-DLBCL is by far the most common form of testicular cancer in men >60 years of age. [2] It usually develops in this age group (median age ~65 years old, range 10–96 years) and presents as a painless testicular mass or swelling in one testis or, in ~6% of cases, both testes: [1] PT-DLBCL is the most common testicular cancer to present with disease in both testicles. [8]
The body has a central vessel surrounded by fibrous tissue, called the fibrovascular core, and it is surrounded by layers of the tumoral cells at the surface of that stalk. The structure is located in open cystic space also lined by tumoral cells. All those structures together are called a Schiller–Duval body and resemble primitive glomerulus.