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The Guinea pig maximisation test (GPMT) is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by B. Magnusson and Albert Kligman in 1969 [ 1 ] and described in their 1970 book Allergic Contact Dermatitis in the Guinea Pig .
The Buehler test is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by Edwin Vernon Buehler in 1965 [1] and further explained in 1980. [2] It is a non-adjuvant test. In the test, guinea pigs are exposed to a high dose of the substance.
In English, the term "guinea pig" is commonly used as a metaphor for a subject of scientific experimentation, or in modern times a subject of any experiment or test. This usage dates back to the early 20th century: the earliest examples cited by the Oxford English Dictionary date from 1913 and 1920. [ 182 ]
Human subject research is systematic, scientific investigation that can be either interventional (a "trial") or observational (no "test article") and involves human beings as research subjects, commonly known as test subjects. Human subject research can be either medical (clinical) research or non-medical (e.g., social science) research. [1]
From the common American guinea pig to the exotic Lunkarya Guinea Pig, these are the guinea pig breeds you should know about.
Currently, rodents are commonly used in animal testing for physiological, pathological and behavioral scientific studies, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate
Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate. [ 96 ] [ 97 ] Mice are widely considered to be the best model of inherited human disease and share 95% of their genes with humans. [ 96 ]
Conservation biologist has believed for years that the New Guinea singing dog was either extinct or close to extinction due to their loss of habitat and contact with village dogs.