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Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. [1] A biological target , also known as the site of action, can be binding proteins, ion channels , DNA , or a variety of other receptors.
It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound and its toxicity.It is used primarily for establishing relationships between exposures in toxicology experiments in animals and the corresponding exposures in humans.
They can either submit one web page at a time, or they can submit the entire site using a sitemap, but it is normally only necessary to submit the home page of a web site as search engines are able to crawl a well designed website. There are two remaining reasons to submit a web site or web page to a search engine: to add an entirely new web ...
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Toxicodynamics (TD) and pharmacodynamics (PD) link a therapeutic agent or toxicant, or toxin (xenobiotic)'s dosage to the features, amount, and time course of its biological action. [11] The mechanism of action is a crucial factor in determining effect and toxicity of the drug, taking in consideration the pharmacokinetic (PK) factors. [ 12 ]
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Wikipedia (along with its sister projects) has become one of the largest websites in the world using a model of love and co-operation that is still almost completely unknown to the wider world. But it is becoming known, for both its principles and achievements – because it is the principles that make the achievements possible.